Human LGR4 / GPR48 protein, His Tag | LG4-H52H3-1mg

Human LGR4 / GPR48 protein, His Tag | LG4-H52H3-1mg| Gentaur Distribution US, UK & Europe

The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, frequently referred to as GPR48) together with its family members LGR5 and -6, bind to R-spondins (RSPOs) -1–4 and result in Wnt signaling potentiation. In addition, LGR4 (as well as LGR5 and -6) is implicated in multiple cancers and promotes invasion and metastasis in colorectal, prostate, and cervical cancer cell lines.

Source: Human LGR4, His Tag (LG4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 -Thr 544 (Accession # Q9BXB1-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ala 25 -Thr 544.

Conjugate: Unconjugated.

Molecular Weight: 58.8 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.8 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 85%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT