Description
Human Laminin 211 E8 Protein, Fc Tag (HPLC verified) | LA8-H5263-1mg| Gentaur Distribution US, UK & Europe
Laminin-α2 is a critical component of the laminin heterotrimer, which along with laminin-β1 or β2 and laminin-γ1 form the structural glycoproteins laminin-211 and laminin-221 in skeletal muscle. Laminin-211 is the most abundant laminin isoform in the basement membrane of adult skeletal muscle. Laminin-211 and -221 polymerize with each other and interact with nidogen and collagen-IV to form the muscle basal lamina. Laminin-211 and laminin-221 bind to muscle cell surface through the α7β1 integrin and α-dystroglycan of the dystrophin glycoprotein complex via their globular C-terminal domains.
Source: Human Laminin 211 E8 Protein, Fc Tag (LA8-H5263) is expressed from human 293 cells (HEK293). It contains AA Leu 1900 - Ala 2722 & Asp 1714 - Leu 1786 & Asp 1528 - Pro 1609 (Accession # P24043 & P07942 & P11047).
Format: Powder.
Tag: N-Fc.
Expression System: HEK293.
Expression Region: Leu 1900 - Ala 2722 & Asp 1714 - Leu 1786 & Asp 1528 - Pro 1609.
Conjugate: Unconjugated.
Molecular Weight: 94.3 kDa & 35 kDa & 35.7 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 94.3 kDa & 35 kDa & 35.7 kDa. The protein migrates as 70-80 Da and 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
