Human KIR2DL2 / CD158b1 / NKAT-6 Protein, Fc Tag | KI2-H5255-1mg

Human KIR2DL2 / CD158b1 / NKAT-6 Protein, Fc Tag | KI2-H5255-1mg| Gentaur Distribution US, UK & Europe

Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells. KIR2DL2 and KIR2DL3, regulate the activation of natural killer cells (NK) by interacting with the human leukocyte antigen-C1 (HLA-C1) group of molecules. KIR2DL2, KIR2DL3 and HLA-C1 are highly polymorphic, with this variation being associated with differences in the onset and progression of some human diseases.

Source: Human KIR2DL2, Fc Tag (KI2-H5255) is expressed from human 293 cells (HEK293). It contains AA His 22 - His 245 (Accession # P43627-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: His 22 - His 245.

Conjugate: Unconjugated.

Molecular Weight: 51.0 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris 100 mM Glycine, 25 mM Argine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT