Human JAB1 / COPS5 Protein, Fc Tag | JA1-H5553-1mg

Human JAB1 / COPS5 Protein, Fc Tag | JA1-H5553-1mg| Gentaur Distribution US, UK & Europe

Jab1, also known as CSN5, is a component of (COP9) signalosome complex (CSN) and reported to be involved in the regulation of cell proliferation, cell-cycle progression, and tumorigenesis. As a component of the COP9 signalosome complex, Jab1 could reciprocally regulate the stability and transcriptional activity of MED1 and might be a MED1 direct target gene mediating the aggressive phenotypes of HER2+tumors.

Source: Human JAB1 Protein, Fc Tag (JA1-H5553) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Ser 334 (Accession # Q92905-1).

Format: Powder.

Tag: C-Fc.

Expression System: InsectCells.

Expression Region: Ala 2 - Ser 334.

Conjugate: Unconjugated.

Molecular Weight: 63.9 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 63.9 kDa. The protein migrates as 33 kDa and 64-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT