Description
Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (MALS verified) | ILR-H5255-1mg| Gentaur Distribution US, UK & Europe
TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
Source: Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (ILR-H5255) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 (IL-7 RA) & Gln 23 - Lys 231 (TSLP R) (Accession # P16871-1 (I66T, V138I) (IL-7RA) & Q9HC73-1 (TSLPR) ).
Format: Powder.
Tag: C-Fc | C-Fc.
Expression System: HEK293.
Expression Region: Glu 21 - Asp 239 (IL-7 RA) & Gln 23 - Lys 231 (TSLP R).
Conjugate: Unconjugated.
Molecular Weight: 51.7 kDa (IL-7 RA) & 50.3 kDa (TSLP R).
Characteristics: Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-7 RA and TSLP R, has a calculated MW of 51.7 kDa (IL-7 RA) and 50.3 kDa (TSLP R). Subunit IL-7 RA is fused with a human IgG1 Fc fragment at the C-terminus and subunit TSLP R is fused with a human IgG1 Fc fragment at the C-terminus. The reducing (R) protein migrates as 60-80 kDa due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
