Human IL-7 R alpha / CD127 Protein, Mouse IgG2a Fc Tag | IL7-H5258-1mg

Human IL-7 R alpha / CD127 Protein, Mouse IgG2a Fc Tag | IL7-H5258-1mg| Gentaur Distribution US, UK & Europe

Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

Source: Human IL-7 R alpha, Mouse IgG2a Fc Tag (IL7-H5258) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 236 (Accession # P16871-1 (I66T, V138I) ).

Format: Powder.

Tag: C-mFc (mIgG2a).

Expression System: HEK293.

Expression Region: Glu 21 - Gly 236.

Conjugate: Unconjugated.

Molecular Weight: 52.0 kDa.

Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT