Human IL-5 R alpha / CD125 Protein, Fc Tag (MALS verified) | ILA-H5269-1mg

Human IL-5 R alpha / CD125 Protein, Fc Tag (MALS verified) | ILA-H5269-1mg| Gentaur Distribution US, UK & Europe

Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125, which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.

Source: Human IL-5 R alpha, Fc Tag (ILA-H5269) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Trp 342 (Accession # Q01344-1).

Format: Powder.

Tag: N-Fc.

Expression System: HEK293.

Expression Region: Asp 21 - Trp 342.

Conjugate: Unconjugated.

Molecular Weight: 63.2 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 63.2 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT