Description
Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin | ILA-H5255-1mg| Gentaur Distribution US, UK & Europe
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Source: Human IL-3 R alpha Protein, Llama IgG2b Fc Tag (ILA-H5255) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1).
Format: Powder.
Tag: C-LlamaFc (LlamaIgG2b).
Expression System: HEK293.
Expression Region: Thr 19 - Arg 305.
Conjugate: Unconjugated.
Molecular Weight: 60.9 kDa.
Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 60.9 kDa. The protein migrates as 45 kDa, 55 kDa and 80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
