Description
Human IL-24 Protein, His Tag (BLI verified) | IL4-H52H4-100ug| Gentaur Distribution US, UK & Europe
Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.
Source: Human IL-24 Protein, His Tag (IL4-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 52 - Leu 206 (Accession # Q13007-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gln 52 - Leu 206.
Conjugate: Unconjugated.
Molecular Weight: 20.0 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.0 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
