Human IL-2 R alpha / CD25 Protein, His Tag | ILA-H52H9-1mg

(No reviews yet) Write a Review
SKU:
716-ILA-H52H9-1mg
Availability:
IN STOCK
Weight:
1.20 KGS
€2,572.00
Frequently bought together:

Description

Human IL-2 R alpha / CD25 Protein, His Tag | ILA-H52H9-1mg| Gentaur Distribution US, UK & Europe

Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

Source: Human IL-2 R alpha, His Tag (ILA-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Cys 213 (Accession # NP_000408).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Glu 22 - Cys 213.

Conjugate: Unconjugated.

Molecular Weight: 23.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.6 kDa. The protein migrates as 34-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT

View AllClose

Additional Information

Size:
1 mg
View AllClose