Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag | ILP-H5256-1mg

Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag | ILP-H5256-1mg| Gentaur Distribution US, UK & Europe

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Source: Human IL-1 RAcP, Fc Tag (ILP-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Ser 21 - Glu 359.

Conjugate: Unconjugated.

Molecular Weight: 65.7 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 65.7 kDa. The protein migrates as 75-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT