Human IL-1 beta / IL-1F2 Protein, Fc Tag (MALS verified) | ILA-H525c-20ug

Human IL-1 beta / IL-1F2 Protein, Fc Tag (MALS verified) | ILA-H525c-20ug| Gentaur Distribution US, UK & Europe

Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96 % amino acid sequence identity with rhesus and 67 % -78 % with canine, mouse and rat IL-1β.

Source: Human IL-1 beta, Fc Tag (ILA-H525c) is expressed from human 293 cells (HEK293). It contains AA Ala 117 - Ser 269 (Accession # P01584-1).

Format: Powder.

Tag: N-Fc.

Expression System: HEK293.

Expression Region: Ala 117 - Ser 269.

Conjugate: Unconjugated.

Molecular Weight: 43.8 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 43.8 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT