Human IgG4 Fc Protein, Tag Free (MALS & SPR verified) | IG4-H5205-200ug

Human IgG4 Fc Protein, Tag Free (MALS & SPR verified) | IG4-H5205-200ug| Gentaur Distribution US, UK & Europe

Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).

Source: Human IgG4 Fc, Tag Free (IG4-H5205) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 327 (Accession # P01861).

Format: Powder.

Tag: Native.

Expression System: HEK293.

Expression Region: Glu 99 - Lys 327.

Conjugate: Unconjugated.

Molecular Weight: 25.8 kDa.

Characteristics: This protein carries no "tag". The protein has a calculated MW of 25.8 kDa. As a result of glycosylation, the protein migrates as 30-32 kDa under reducing (R) condition, and 28-30 kDa and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE).

Purity: 95%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT