Human IGFBP-3 R / TMEM219 Protein, Fc Tag (MALS verified) | IGR-H5259-100ug

Human IGFBP-3 R / TMEM219 Protein, Fc Tag (MALS verified) | IGR-H5259-100ug| Gentaur Distribution US, UK & Europe

IGFBP-3 R, also know as TMEM219, is a cell death receptor specific for IGFBP3. IGFBP-3R is expressed on the cell surface, interacts specifically with IGFBP-3 but not other IGFBP species. It activates initiator caspase-8, and mediates IGFBP-3-induced apoptosis in vitro and tumor suppression in vivo.

Source: Human IGFBP-3 R, Fc Tag (IGR-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 39 - Arg 204 (Accession # Q86XT9-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Ser 39 - Arg 204.

Conjugate: Unconjugated.

Molecular Weight: 44.3 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.3 kDa. The protein migrates as 58-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT