Human HTT Protein, MBP, His Tag (MALS verified) | HTT-H51M5-500ug

Human HTT Protein, MBP, His Tag (MALS verified) | HTT-H51M5-500ug| Gentaur Distribution US, UK & Europe

Huntingtin is the protein coded for by the HTT gene. Autosomal dominant mutation in the Huntingtin (Htt) protein is the cause of Huntington’s Disease (HD). In HD, the polyglutamine (polyQ) domain in the N-terminal sequenceof the protein is expanded beyond a threshold of 36 glutamines. mutant polyQ expansion strongly correlates in an inverse manner to disease age of onset.

Source: Human HTT, MBP, His Tag (HTT-H51M5) is expressed from E. coli cells. It contains AA Met 1 - Glu 82 (Accession # P42858-1).

Format: Powder.

Tag: N-MBP & C-10×His.

Expression System: E. coli.

Expression Region: Met 1 - Glu 82.

Conjugate: Unconjugated.

Molecular Weight: 52.7 kDa.

Characteristics: This protein carries a MBP tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.7 kDa. The protein migrates as 60-63 kDa under reducing (R) condition (SDS-PAGE).

Purity: 95%.

Buffer: 20 mM HEPES, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT