Description
Human HLA-A*03:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer, MALS verified) | HLS-H52H4-25ug| Gentaur Distribution US, UK & Europe
The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRAS (VVGAGGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGAGGVGK peptide of the KRAS.
Source: Human HLA-A*03:01&B2M&KRAS (VVGAGGVGK) Complex Protein (HLS-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAGGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVGAGGVGK).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAGGVGK peptide.
Conjugate: Unconjugated.
Molecular Weight: 34.2 kDa and 11.7 kDa.
Characteristics: Human HLA-A*03:01&B2M&KRAS (VVGAGGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRAS peptide. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.2 kDa and 11.7 kDa. The protein migrates as 40-42 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
