Description
Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Tetramer Protein (MALS verified) | HLG-H52E5-25ug| Gentaur Distribution US, UK & Europe
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. The Human HLA-A*0201 Glycipan 3 (FVGEFFTDV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and FVGEFFTDV peptide of the Glycipan 3 .
Source: Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Tetramer Protein (HLG-H52E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & FVGEFFTDV peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & FVGEFFTDV).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 25 - Thr 305 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & FVGEFFTDV peptide.
Conjugate: Unconjugated.
Molecular Weight: 36.0 kDa and 13.8 kDa.
Characteristics: Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Tetramer Protein is assembled by biotinylated monomer (HLG-H82E4) and streptavidin. Biotinylated Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Complex Protein is produced by co-expression of HLA and B2M loaded with Glypican 3 peptide. Biotinylated Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.0 kDa and 13.8 kDa. The protein migrates as 42-45 kDa, 15 kDa and 14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
