Description
Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (MALS verified) | HE2-H5254-1mg| Gentaur Distribution US, UK & Europe
The Human Epidermal Growth Factor Receptor 2 (HER2) and HER3 form a potent pro-oncogenic heterocomplex upon binding of growth factor neuregulin-1β (NRG1β). The HER2/HER3 extracellular dimer dynamics likely have important implications for modulating receptor activity.
Source: Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (HE2-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 & Ser 20 - Thr 643 (Accession # P04626 & P21860).
Format: Powder.
Tag: C-Fc | C-Fc.
Expression System: HEK293.
Expression Region: Thr 23 - Thr 652 & Ser 20 - Thr 643.
Conjugate: Unconjugated.
Molecular Weight: 95.9 kDa & 94.9 kDa.
Characteristics: Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag, produced by co-expression of HER2 and ErbB3, has a calculated MW of 95.9 kDa & 94.9 kDa. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
