Human GM-CSF R alpha Protein, His Tag (SPR verified) | GRA-H52H7-100ug

Human GM-CSF R alpha Protein, His Tag (SPR verified) | GRA-H52H7-100ug| Gentaur Distribution US, UK & Europe

GM-CSF R alpha (Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

Source: Human GM-CSF R alpha, His Tag (GRA-H52H7) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Gly 320 (Accession # P15509-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Glu 23 - Gly 320.

Conjugate: Unconjugated.

Molecular Weight: 36.4 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT