Description
Human Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin | GP3-H5257-100ug| Gentaur Distribution US, UK & Europe
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Source: Human Glypican 3, Llama IgG2b Fc Tag, low endotoxin (GP3-H5257) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # P51654-1).
Format: Powder.
Tag: C-LlamaFc (LlamaIgG2b).
Expression System: HEK293.
Expression Region: Gln 25 - His 559.
Conjugate: Unconjugated.
Molecular Weight: 38.1 kDa and 50.5 kDa.
Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 50.5 kDa respectively. The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
