Description
Human GITR / TNFRSF18 Protein, Fc Tag | GIR-H5254-1mg| Gentaur Distribution US, UK & Europe
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Source: Human GITR, Fc Tag (GIR-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Gln 26 - Glu 161.
Conjugate: Unconjugated.
Molecular Weight: 41.0 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.0 kDa. The protein migrates as 45-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
