Human GCGR / Glucagon receptor Protein, Fc Tag (MALS verified) | GCR-H53H3-50ug

Human GCGR / Glucagon receptor Protein, Fc Tag (MALS verified) | GCR-H53H3-50ug| Gentaur Distribution US, UK & Europe

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of  type 2 diabetes mellitus (T2DM)  . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.

Source: Human GCGR Protein, Fc Tag (GCR-H53H3) is expressed from CHO cells. It contains AA Ala 26 - Lys 136 (Accession # P47871-1).

Format: Powder.

Tag: C-Fc.

Expression System: CHO.

Expression Region: Ala 26 - Lys 136.

Conjugate: Unconjugated.

Molecular Weight: 39.5 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. The protein migrates as 52-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT