Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified) | FRD-H52H3-100ug

Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified) | FRD-H52H3-100ug| Gentaur Distribution US, UK & Europe

Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.

Source: Human Frizzled-10, His Tag (FRD-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Gly 161 (Accession # Q9ULW2-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ile 21 - Gly 161.

Conjugate: Unconjugated.

Molecular Weight: 18.0 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.0 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT