Human FOLR4 Protein, His Tag (MALS verified) | FO4-H52H3-1mg

Human FOLR4 Protein, His Tag (MALS verified) | FO4-H52H3-1mg| Gentaur Distribution US, UK & Europe

FOLR4, also know as Sperm-egg fusion protein Juno (IZUMO1R) is receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

Source: Human FOLR4, His Tag (FO4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ser 228 (Accession # A6ND01-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gly 20 - Ser 228.

Conjugate: Unconjugated.

Molecular Weight: 25.8 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, 500 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT