Description
Human FGL1 (64-312) Protein, Fc Tag | FG1-H5254-1mg| Gentaur Distribution US, UK & Europe
Fibrinogen-like protein 1 (FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.
Source: Human FGL1 (64-312), Fc Tag (FG1-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 64 - Ile 312 (Accession # Q08830-1).
Format: Powder.
Tag: N-Fc.
Expression System: HEK293.
Expression Region: Asp 64 - Ile 312.
Conjugate: Unconjugated.
Molecular Weight: 114.6 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 114.6 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
