Description
Human FGF19 Protein, Fc Tag | FG9-H5253-1mg| Gentaur Distribution US, UK & Europe
Fibroblast growth factor (FGF) 19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.
Source: Human FGF19, Fc Tag (FG9-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Lys 216 (Accession # O95750-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Leu 25 - Lys 216.
Conjugate: Unconjugated.
Molecular Weight: 47.9 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
