Description
Human FGF-4 Protein, His Tag | FG4-H51H3-100ug| Gentaur Distribution US, UK & Europe
Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.
Source: Human FGF-4 Protein, His Tag (FG4-H51H3) is expressed from E. coli cells. It contains AA Ser 54 - Leu 206 (Accession # P08620-1).
Format: Powder.
Tag: C-10×His.
Expression System: E. coli.
Expression Region: Ser 54 - Leu 206.
Conjugate: Unconjugated.
Molecular Weight: 19.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.8 kDa. The protein migrates as 23-24 kDa under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: MOPS, Na2SO4, Arginine and EDTA.
Storage Conditions: -20℃.
Shipping Conditions: RT
