Description
Human FGF-3 / HBGF-3 Protein, His Tag | FG3-H51H9-1mg| Gentaur Distribution US, UK & Europe
Fibroblast growth factor 3 (FGF3), belonging to the family of fibroblast growth factors (FGFs), regulates several developmental processes, including brain patterning, branching morphogenesis and limb development, by binding, dimerizing and activating cell surface FGF receptors (FGFRs). FGF/FGFR complexes have been demonstrated to act as driving oncogenes in certain types of cancer to maintain the malignant properties of tumor cells in a cell autonomous manner. According to previous studies, it is speculated that FGF3 is upregulated in breast cancer and accelerates tumor growth and angiogenesis. Consequently, FGF3 has been considered as a potential target for breast cancer therapy.
Source: Human FGF-3, His Tag (FG3-H51H9) is expressed from E. coli cells. It contains AA Ala 18 - His 239 (Accession # P11487-1).
Format: Powder.
Tag: C-10×His.
Expression System: E. coli.
Expression Region: Ala 18 - His 239.
Conjugate: Unconjugated.
Molecular Weight: 27.0 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 30 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 20 mM Mops, 0.2 M Arginine, 2 mM TCEP, 2 mM EDTA, pH7.3.
Storage Conditions: -20℃.
Shipping Conditions: RT
