Description
Human Exodus-2 | 90132-A | Gentaur US, UK & Europe Disrtribition
Category: Cytokine
Application: N/A
Background: Exodus-2, which is a member of the family of CC- Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. Exodus-2 selectively stimulates the chemotaxis of adult T-lymphocytes and is expressed preferentially in lymph node tissue. Exodus-2 is critical for adult T-cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T-cell trafficking through nodal tissue.
Description: Recombinant Exodus-2 is a disulfide-linked homodimeric protein consisting of 112 amino acid residues, and migrates as an approximately 12 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Exodus-2 mature chain was expressed in E. coli.
Product Type: Protein
Shippement Condition: gel packs or dry ice
