Human Eotaxin-1 (CCL11 ) | 90127-A

Human Eotaxin-1 (CCL11 ) | 90127-A | Gentaur US, UK & Europe Disrtribition

Category: Cytokine

Application: N/A

Background: Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils .

Description: Recombinant Eotaxin-1 is a disulfide-linked homodimeric protein consisting of 75 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-1 mature chain was expressed in E. coli.

Product Type: Protein

Shippement Condition: gel packs or dry ice