Description
Human ENPP-2 / Autotaxin Protein, His Tag (active enzyme) | EN2-H5241-250ug| Gentaur Distribution US, UK & Europe
Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.
Source: Human ENPP-2, His Tag (EN2-H5241) is expressed from human 293 cells (HEK293). It contains AA Asp 49 - Ile 863 (Accession # NP_001035181).
Format: Powder.
Tag: N-6×His.
Expression System: HEK293.
Expression Region: Asp 49 - Ile 863.
Conjugate: Unconjugated.
Molecular Weight: 94.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 94.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
