Description
Human EDNRB Full Length Protein (VLP) | EDB-H52P7-500ug| Gentaur Distribution US, UK & Europe
Endothelin Receptor B (EDNRB) is a type of G protein-coupled Receptor with the N-terminus located outside the cell. It's widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipid-dependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has pro-tumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, anti-apoptosis, promoting angiogenesis and promoting tumor metastasis.
Source: Human EDNRB Full Length Protein-VLP (EDB-H52P7) is expressed from human 293 cells (HEK293). It contains AA Glu 27 - Ser 442 (Accession # P24530-1).
Format: Liquid.
Tag: N/A.
Expression System: HEK293.
Expression Region: Glu 27 - Ser 442.
Conjugate: Unconjugated.
Molecular Weight: N/A.
Characteristics: This protein .
Purity: N/A.
Buffer: PBS, Arginine, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
