Description
Human DLL4 Protein, Fc Tag, premium grade | DL4-H5259-1mg| Gentaur Distribution US, UK & Europe
Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
Source: Human DLL4, Fc Tag (DL4-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Ser 27 - Pro 524.
Conjugate: Unconjugated.
Molecular Weight: 80.9 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 80.9 kDa. The protein migrates as 95-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 100 mM Glycine, 150 mM NaCl, 25 mM Arginine, 50 mM Tris, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
