Human DLL1 / Delta1 Protein, His Tag | DL1-H52H8-100ug

Human DLL1 / Delta1 Protein, His Tag | DL1-H52H8-100ug| Gentaur Distribution US, UK & Europe

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

Source: Human DLL1, His Tag (DL1-H52H8) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Gly 540 (Accession # NP_005609).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gln 18 - Gly 540.

Conjugate: Unconjugated.

Molecular Weight: 58.4 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT