Description
Human CXCL4 / PF4 Protein, His Tag | CX4-H52H9-100ug| Gentaur Distribution US, UK & Europe
CXCL4, or Platelet factor 4 (PF4), is a small cytokine belonging to the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. CXCL4 is chemotactic for neutrophils and monocytes and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment.
Source: Human CXCL4, His Tag (CX4-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Ser 101 (Accession # P02776-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Glu 32 - Ser 101.
Conjugate: Unconjugated.
Molecular Weight: 9.7 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 9.7 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 10 mM Sodium Citrate, 150 mM NaCl, pH5.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
