Human CLEC4C / BDCA2 Protein, Fc Tag | CLC-H5254-100ug

Human CLEC4C / BDCA2 Protein, Fc Tag | CLC-H5254-100ug| Gentaur Distribution US, UK & Europe

CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal (beta1-3/4) GlcNAc (beta1-2) Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.

Source: Human CLEC4C, Fc Tag (CLC-H5254) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).

Format: Powder.

Tag: N-Fc.

Expression System: HEK293.

Expression Region: Asn 45 - Ile 213.

Conjugate: Unconjugated.

Molecular Weight: 46.4 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 46.4 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT