Description
Human Claudin-9 / CLDN9 Full Length Protein (VLP) | CL9-H52P5-100ug| Gentaur Distribution US, UK & Europe
Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus; it enables HCV entry into target cells just as efficiently as CLDN1.
Source: Human Claudin-9 Full Length Protein-VLP (CL9-H52P5) is expressed from human 293 cells (HEK293). It contains AA Met 1 -Val 217 (Accession # O95484-1).
Format: Liquid.
Tag: -.
Expression System: HEK293.
Expression Region: Met 1 -Val 217.
Conjugate: Unconjugated.
Molecular Weight: N/A.
Characteristics: This protein .
Purity: N/A.
Buffer: PBS, Arginine, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
