Description
Human Claudin-1 Protein, Flag, His Tag (Detergent) | CL1-H55D8-500ug| Gentaur Distribution US, UK & Europe
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008].
Source: Human Claudin-1 Protein, Flag, His Tag (CL1-H55D8) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Val 211 (Accession # O95832).
Format: Liquid.
Tag: N-Flag & N-10×His.
Expression System: InsectCells.
Expression Region: Ala 2 - Val 211.
Conjugate: Unconjugated.
Molecular Weight: 25.8 kDa.
Characteristics: This protein carries a flag tag at the N-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.8 kDa. The protein migrates as 8 kDa, 10 kDa, 20 kDa and 22-23 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
