Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc, Flag Tag&Mouse IgG2a Fc, His Tag (MALS verified) | CDB-H52W3-100ug

Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc, Flag Tag&Mouse IgG2a Fc, His Tag (MALS verified) | CDB-H52W3-100ug| Gentaur Distribution US, UK & Europe

CD79a and CD79b heterodimers are the important signaling components of B cell receptor (BCR) complex which plays a crucial role in B cell development and antibody production. BCR complexes are composed of a ligand-binding receptor (membrane immunoglobulin; mIg), non-covalently associated with the signaling com-ponent, a disulfide-linked heterodimer of CD79a (Igα) and CD79b (Igβ). Both CD79 subunits consist of an Ig-like domain, a transmembrane (TM) region, and a longer cytoplasmic tail (CYT) containing an immune-receptor tyrosine-based activation motif (ITAM).

Source: Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc, Flag Tag&Mouse IgG2a Fc, His Tag (CDB-H52W3) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Arg 143 (CD79A) & Ala 29 - Asp 159 (CD79B) (Accession # P11912-1 (CD79A) & P40259-1 (CD79B) ).

Format: Powder.

Tag: C-mFc (mIgG2a) & C-Flag | C-mFc (mIgG2a) & C-10×His.

Expression System: HEK293.

Expression Region: Leu 33 - Arg 143 (CD79A) & Ala 29 - Asp 159 (CD79B).

Conjugate: Unconjugated.

Molecular Weight: 43.8 kDa & 46.7 kDa.

Characteristics: Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc, Flag Tag&Mouse IgG2a Fc, His Tag is produced by co-expression of CD79A and CD79B, has a calculated MW of 43.8 kDa (CD79A) and 46.7 kDa (CD79B). Subunit CD79A carries a mouse IgG2a Fc fragment at the C-terminus, followed by a flag tag and subunit CD79B carries a mouse IgG2a Fc fragment at the C-terminus, followed by a polyhistidine tag. The protein migrates as 120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT