Human CD45RA / PTPRC protein, His Tag | CD5-H52H9-100ug

Human CD45RA / PTPRC protein, His Tag | CD5-H52H9-100ug| Gentaur Distribution US, UK & Europe

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Source: Human CD45RA / PTPRC protein, His Tag (CD5-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Lys 482 (Accession # P08575-8).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gln 26 - Lys 482.

Conjugate: Unconjugated.

Molecular Weight: 53.2 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT