Description
Human CD45 / PTPRC Protein, Llama IgG2b Fc Tag, low endotoxin | CD5-H5259-1mg| Gentaur Distribution US, UK & Europe
CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
Source: This protein carries a human IgG2a Fc tag at the C-terminus. Human CD45, Llama IgG2b Fc Tag, low endotoxin (CD5-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Lys 577 (Accession # P08575-3).
Format: Powder.
Tag: C-LlamaFc (LlamaIgG2b).
Expression System: HEK293.
Expression Region: Gln 26 - Lys 577.
Conjugate: Unconjugated.
Molecular Weight: 88.6 kDa.
Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 88.6 kDa. The protein migrates as 200-250 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
