Description
Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (MALS verified) | CDG-H52W9-1mg| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Human CD3E&CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDG-H52W9) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G) (Accession # P07766-1 (CD3E) & P09693-1 (CD3G) ).
Format: Powder.
Tag: C-Fc & C-6×His | C-Fc & C-Flag.
Expression System: HEK293.
Expression Region: Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G).
Conjugate: Unconjugated.
Molecular Weight: 39.2 kDa (CD3E) & 38.6 kDa (CD3G).
Characteristics: Human CD3E&CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus, followed by a polyhistidine tag, and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus, followed by a Flag tag. The predicted N-terminus is Asp 23 (CD3E) & Gln 23 (CD3G). The reducing (R) heterodimer protein migrates as 40-50 kDa due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
