Human CD3 epsilon & CD3 delta Heterodimer Protein, His Tag&Tag Free (MALS verified) | CDD-H52W1-1mg

Human CD3 epsilon & CD3 delta Heterodimer Protein, His Tag&Tag Free (MALS verified) | CDD-H52W1-1mg| Gentaur Distribution US, UK & Europe

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Source: Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (CDD-H52W1) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D) ).

Format: Powder.

Tag: C-8×His | Native.

Expression System: HEK293.

Expression Region: Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D).

Conjugate: Unconjugated.

Molecular Weight: 16.6 kDa (CD3E) and 13.4 kDa (CD3D).

Characteristics: Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free is produced by co-expression of CD3E and CD3D, has a calculated MW of 16.6 kDa (CD3E) and 13.4 kDa (CD3D). Subunit CD3E is fused with a polyhistidine tag at the C-terminus and subunit CD3D contains no tag. The reducing (R) heterodimer protein migrates as 25-30 kDa (CD3E) and 20 kDa and 22 kDa (CD3D) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT