Description
Human CD28H / IGPR-1 Protein, His Tag | CDH-H52H3-1mg| Gentaur Distribution US, UK & Europe
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1, is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue, the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Source: Human CD28H, His Tag (CDH-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Gly 150 (Accession # Q96BF3-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Leu 23 - Gly 150.
Conjugate: Unconjugated.
Molecular Weight: 15.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.9 kDa. The protein migrates as 22-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT