Description
Human CD133 Full Length Protein, His Tag (Nanodisc) | CD3-H52H1-20ug| Gentaur Distribution US, UK & Europe
Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Source: Human CD133 Full Length, His Tag (Nanodisc) (CD3-H52H1) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - His 865 (Accession # O43490-1).
Format: Liquid.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 20 - His 865.
Conjugate: Unconjugated.
Molecular Weight: 97.2 kDa.
Characteristics: The CD133 carries a polyhistidine tag at the C-terminus with calculated MW of 97.2 kDa and migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. The membrane scaffold protein (MSP1D1) has calculated MW of 24.7 kDa, and it migrates as 25 kDa under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: 50 mM HEPES, 150 mM NaCl, pH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
