Description
Human CCR5 Protein, Flag, His Tag (Detergent) | CC5-H52D1-500ug| Gentaur Distribution US, UK & Europe
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Source: Human CCR5, Flag, His Tag (CC5-H52D1) is expressed from human 293 cells (HEK293). It contains AA Asp 2 - Arg 223 & Glu 227 - Arg 319 (Accession # P51681-1 (C58Y, G163N, A233D, K303E) ).
Format: Liquid.
Tag: N-Flag & C-10×His.
Expression System: HEK293.
Expression Region: Asp 2 - Arg 223 & Glu 227 - Arg 319.
Conjugate: Unconjugated.
Molecular Weight: 46.0 kDa.
Characteristics: This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 33-35 kDa and 40-45 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 85%.
Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
