Description
Human CCL5/RANTES Protein, Fc Tag (MALS verified) | CC5-H5251-1mg| Gentaur Distribution US, UK & Europe
C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.
Source: Human CCL5, Fc Tag (CC5-H5251) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ser 91 (Accession # P13501-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Ser 24 - Ser 91.
Conjugate: Unconjugated.
Molecular Weight: 34.4 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.4 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
