Description
Human CCL3 / MIP-1 alpha Protein, His Tag | CC3-H5249-50ug| Gentaur Distribution US, UK & Europe
CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Source: Human CCL3, His Tag (CC3-H5249) is expressed from E. coli cells. It contains AA Ser 24 - Ala 92 (Accession # P10147-1).
Format: Powder.
Tag: N-10×His.
Expression System: E. coli.
Expression Region: Ser 24 - Ala 92.
Conjugate: Unconjugated.
Molecular Weight: 9.7 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 9.7 kDa. The protein migrates as 12-13 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 20 mM Tris, 150 mM NaCl, 0.2 M Arginine, 1 mM EDTA, pH8.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
