Description
Human Cadherin-6 / KCAD / CDH6 Protein, His Tag | CA6-H5229-100ug| Gentaur Distribution US, UK & Europe
Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
Source: Human Cadherin-6, His Tag (CA6-H5229) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # AAH00019).
Format: Powder.
Tag: C-6×His.
Expression System: HEK293.
Expression Region: Thr 19 - Ala 615.
Conjugate: Unconjugated.
Molecular Weight: 67.2 kDa & 63.4 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The Human Cadherin-6 will be further processed into mature form (Ser 54-Ala 615). The protein has a calculated MW of 67.2 kDa (pro-form) and 63.4 kDa (mature-form). The protein migrates as 86-96 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 85%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
