Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified) | CA6-H5258-1mg

Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified) | CA6-H5258-1mg| Gentaur Distribution US, UK & Europe

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Source: Human Cadherin-6 Protein, Fc Tag (CA6-H5258) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Thr 19 - Ala 615.

Conjugate: Unconjugated.

Molecular Weight: 92.8 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The Human Cadherin-6 will be further processed into mature form (Ser 54 - Ala 615). The protein has a calculated MW of 92.8 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT